SPECT Ioflupane123I (DaTscan), 99mTc (TRODAT) and Ioflupane with Myocardial Scintigraphy 123I (MIBG) for Diagnosis of Parkinson’s Disease

Parkinson’s disease (PD) is one of the most common neurological disorder diseases which takes place when brain cells gradually die. PD considered a challengeable because similarities between and other disorders. For this reason, there are several ways to diagnose PD. Nuclear medicine can be solution distinguish some disorders The aim review understand differences three radiopharmaceuticals used list advantages disadvantages using each radiopharmaceutical. This includes studies from 2014 2019. Every study published before was excluded. database for search found in PubMed. English filters best matches were minimize outcomes. comparison nuclear agents established according main points: availability length scan, sensitivity specificity, visual evolution. It would appear that TRODAT 99mTc helpful departments cannot offer, especially 123I. However, MIBG as biomarker increases specificity studies. 123I with biomarker. Moreover, applying PET/CT studied researched along agents. More research needed relation cardiac uptake